Gilson introduces FTLC system
Posted on | November 25, 2009 | Comments Off
Gilson, Inc., an industry leader in purification systems for HPLC, SPE and GPC clean-up, introduces a solution that will remove 95% water content in fractions thus decreasing dry-down time. Gilson’s Fraction Trapping Liquid Chromatography (FTLC) System is unlike any system on the market today and incorporates the durability of the GX-271 Liquid Handler/Injector, the power of three 306 HPLC Pumps and the precision of the 155 UV/VIS Detector with the ability for column switching via the VALVEMATE® II Valve Actuator.
The Fraction Trapping Liquid Chromatography (FTLC) System is unlike any other product on the market today. The FTLC System is ideally suited for processing fractions greater than 25 mL volume and sample masses up to 500 mg that have been purified on virtually any preparative HPLC system. The collected fractions are re-processed on the FTLC System. While the compounds are trapped on the column, the water content passes through to waste. Washing steps can also be performed for removal of salts, buffers and mobile phase modifiers such as TFA, which can hinder further LC/MS analysis. Fractions containing greater than 50% water content can be processed and collected in 100% organic solvent. This allows for fast dry-down times at lower temperatures for samples that are heat-sensitive, thereby eliminating degradation. Dry-down times of 12–24 hours can be reduced to less than 30 minutes.
They claim it will “Increase Speed of Dry-down while Removing Water Content, Salts, Buffers and Modifiers”. With the introduction of UPLC by Waters, and FTLC by Gilson, it seems like Liquid Chromatography still has a few tricks up its sleeve.
