Dissolution Solutions Network

News, Stories and Commentary from the Pharma Lab

Dissolution Testing: Salicylic Acid

Dear DSN, I have read that they are getting rid of Salicylic Acid tablets for Calibration of dissolution apparatus. What is your opinion on this? A few years back, a few individuals in the PhRMA study claimed that Salicylic Acid was not sensitive to mechanical parameters.  While it is true that Salicylic acid is not […]

Guide To HPLC Troubleshooting

Today I had my car break down on the way to work. This is an event which causes stress to the average person. But almost everyone has had to deal with this one time or another. Chemist as well, must deal with HPLC breakdowns. The average chemist has his or her day planned out before or […]

HPLC Troubleshooting Guide

How to identify, isolate, and correct the most common HPLC problem Although HPLC method development has been improved by advances in column technology and instrumentation, problems still arise. In this guide we offer you a systematic means of isolating, identifying, and correcting many typical problems. The important segments of an HPLC system are the same, […]

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