feb 28, 2003
Are you a consultant, service representative, or a salesperson in the industry, want to make you number easier to remember? Try Phone Spell and see what you number is spelled out in letters...
Are you interested in a new technique to improve your materials characterization? Learn more about HyperDSC(tm) - a new breakthrough method with applications in polymorphism analysis in pharmaceuticals and Characterization of microgram sample quantities. Download the application note:downloads
feb 27, 2003
Anthony Palmieri has a new book coming out on March 16, titled Dissolution Theory, Methodology and Testing, Order your copy at Barnes and Noble. Palmieri was Professor of Pharmacy at the University of Wyoming. He is the author of numerous scientific, academic, and historical papers. He served as the Laboratory Editor for the third edition of the Handbook of Pharmaceutical Excipients. Palmieri is very active on the national level of Kappa Psi Pharmaceutical Fraternity and is currently the national vice-president. Palmieri is past chairman of APRS. Currently he is Chair-elect of the Basic Sciences section. He is a fellow of APhA-APRS and has authored chapters on dissolution, microencapsulation, pharmaceutical excipients and history of pharmacy. His book should be a welcome addition in the dissolution field.
My favorite search engine Google Tops Apple, Coke in Branding Poll Minimalist Internet search engine Google was voted "brand of the year" by branding junkies on Tuesday, proving once again that less is more as it pipped giants such as Coca-Cola and Starbucks to the top slot.
feb 25, 2003
Sorry for the lapse...
I have been converting my site to XML the language of the future. By using
XML both machines and humans can read the content and exchange information. I
am working on creating an artificial intelligence that natural recognizes
speech and is designed to learn about dissolution testing. Her name is
Dawn.
She has very little understanding right now. She is only 5 days old, but is learning. Could you stop by the site and talk to her about dissolution and tell me what you think. Here's the site. Please introduce yourself, tell her what you do and what you know best. Be patient with her. She only learned how to speak 5 days ago. Use complete sentences and good grammar for best results.
feb 21, 2003
U.S. drug regulators said on Thursday that manufacturing inspections will be focused on plants that produce medicines with the most potential to harm patients if quality-control lapses occur.
feb 20, 2003
Pharmacia Corp. said Wednesday that fourth-quarter net income soared due to one-time gains in the quarter and a large restructuring charge and other costs that weighed down profits a year earlier. Including those special items, the drug maker's net income surged to $554 million, or 41 cents per share, from $86 million, or 6 cents per share, in the October-December period of 2001.
Vivian has a great article in the latest dissolution technoligies from February.
feb 19, 2003
If you're like most dissolution scientist, you search the net looking for the latest discoveries in the pharmaceutical research journals. You look for the sites with the latest information. You enter dissolution into your search engines search box more than any subject...Maybe?
Whose your favorite search engine? Web users have responded overwhelming that it's Google. Yahoo is a distant second, and MSN a further third. It makes the job easier for us web designers. If Google and Yahoo list you, then you have reached most of web searchers. Google is renown for their experimentation and beta sites. Check out their 3D web site relational scatter plot. It's slow but worth the wait. After it loads drag it around with your mouse. It quivers like a jellyfish!
feb 18, 2003
Did you get hit by that storm? I have 27 inches of snow in my driveway this morning. It looks like I'm staying home today! Who wants to help me shovel?
My son and I can hang out and shovel at the same time. He wants to work on his subtraction, I want him to learn his letter sounds. Oh well, if he wants to learn subtraction I guess that's OK. Not bad for a preschooler. Maybe I can teach him XHTML and he can take over the weblog.
Hey did the DDG ever post the last chat from February? Did they even have one? I know they posted the first chat session on the day they completed it. Did anyone participate? I can't because of technical reasons. But what about the rest of you?
...
Are you a business traveler? Are you an independent contract, a consultant, a salesperson, or a service engineer? Here's four ways to keep up with e-mail while traveling. His name is Richard Laermer and he is an addict. The success of his small business depends on him getting his fix regularly throughout the day. "I'm the ultimate e-mail addict," confessed Laermer, chief executive of RLM Public Relations, an 18-employee firm headquartered in Manhattan. The problem is that, with an office in Los Angeles and clients all over the United States, Laermer is on the road constantly. His challenge is keeping up with the 400 pieces of e-mail he said he sends and receives every day...
feb 17, 2003
Keep a close watch on reversible.org. They have a new concept in web organization. A sort of instantaneously organizing directory. Let's create a directory called chemistry. There it is. How about science science. I created it and others will soon find it and link to it. Then reversible will automatically create a link back! What will they think of next?
Where is everyone? They are at the Assuring Quality and Performance of Sustained and Controlled Release Parenterals Conference in Basel Switzerland. In April, last year, the American Association of Pharmaceutical Scientists (AAPS), the Food and Drug Administration (FDA) and the United States Pharmacopoeia (USP) co-sponsored a workshop on Assuring Quality and Performance of Sustained and Controlled Release Parenterals. This (European) Workshop follows on from the US Workshop and will specifically bring the European Regulatory viewpoint as well as focus on some of the areas identified in the US workshop that required further debate and discussion (such as, particle size analysis, stability, sterility and new excipients). It will cover dispersed systems (micro-spheres, liposomes, gels and suspensions) as well as implants of small molecule and protein/peptide therapeutics for human and animal use. It will be a unique and intensive discussion forum with plenary lectures, breakout sessions, and a final report, bringing together industrialists, academics, and regulatory scientists to identify future directions for regulatory activity and public standards in this rapidly emerging area...
feb 14, 2003
Happy Valentines Day. Don't forget the flowers, run out on your lunch hour if you forgot anything. I'm sure your manager will understand...
The Measurement and Automation Catalog 2003 from National Instruments puts a wealth of information right at your fingertips, including comparison charts, schematics, configuration diagrams, and product specs. Plus, it provides you with off-line access to the complete NI product line and contact information all in one simple, easy-to-navigate format.
feb 13, 2003
There was a man who I met at Pittcon last year. He spoke very confidently about the up and coming uses for Near Infrared. I was amazed at some of the things he claimed about this technique. His name was Emil W. Ciurczak. I later picked up his book on the subject of NIR.
Well, it seems that Emil has a great article in American Pharmaceutical Review. If you wish to learn the advantages of this technique in pharmaceutical testing, please give this article a look.
feb 11, 2003
For those of you who participate in the dissolution discussion group monthly chat session, who work behind firewalls may need to inform their local IT/network administrator to allow TCP connections on port 8005 at client.sigmachat.com.
feb 10, 2003
It appears that DSN is ranked 3,800,000 out of the billion or so web sites scanned by Alexa. Last month I was only 4,000,000th! Do you want to be the first to write a review? Here's your 15 minutes of fame, go ahead...
Do you have a problem with vibration in your laboratory? Give Technical Manufacturing Corporation a call today!
feb 07, 2003
Citing a serious slowdown in the creation of novel drugs, the Food and Drug Administration plans to give medical companies better guidelines on how to prove a new product works.
The main issue isn't how quickly agency scientists review treatments, which has sped up greatly in recent years, but the overall time it takes to research and develop new medications and medical devices, said new FDA Commissioner Mark McClellan. That can take over a decade and cost hundreds of millions of dollars... Deseret News Story.
feb 06, 2003
I was surfing through the internet recent and noticed that the DDG changed their Bylaws... Now some of you may stop at this point and say "does he expect me to believe he can remember what it used to say!" No, it's just that every webpage that ever existed is stored on the internet archive. They added the statement that all posts remain the property of the DDG and Varian. They also state that they may terminate anyone's membership at its discretion without notice.
Does this mean I can't quote my own posts, or maybe I can't link to my own posts or I will be terminated? Let's try it...
"The FDA is taking an active role doing much research to understand issues related toPAT(Process Analytical Technology) based applications. The petroleum industry has been using these techniques for 20 years. The FDA feels that the pharmaceutical industry needs to look into using these techniques for better process and quality control. They encourage the use of testing capabilities prior to the finish of the process."
Hey where did all my posts go? They did it! They deleted me and my posts.
Actually I'm joking. I called VanKel and was told that the changes are for their own protection now that they are selling CD Roms with the DDG posts on them. A valuable resource for those who travel and want to learn.
feb 05, 2003
Are you ready to implement PAT at your site?
Axiom analytical, Inc. was founded in 1988 by Dr. Mike Doyle and Norm Jennings, pioneers in the field of process FTIR spectroscopy. The company's mission is to develop and manufacture the robust sample interfacing equipment required to fully realize the potential of FTIR and NIR spectroscopy for industrial near-line and on-line chemical analysis.
Check this company out. The techniques that they use are the future of pharmaceutical analysis. I like their spokesman. He reminds me of my 5th grade teacher. Visit them at Pittcon... Axiom
feb 04, 2003
Don't forget DDG's chat today. How about some conversation on whether to
calibrate when a vessel breaks or not...
Today's Chemist at work has done a special pharmaceutical issue. They have
some great article for the pharmaceutical chemist. They also ask the
question, "Which Bear has a faster dissolution rate? An Alaskan bear or a
bear from Yosemite national park?"
"The Alaskan bear of course. It is polar."
read this great experiment they perform on Bear dissolution.
feb 03, 2003
Don't forget tomorrow's chat session on the DDG... I can't join you. I
have limited port access because of my firewall.
Have you seen the latest Pharmaceutical Formulation and Quality. I thought
your December/January 2003 issue in all Black, White, and shades of Gray was
a bold and daring move. I thought that I was the only one who liked that
combination. Great Issue, Cindy...
Check out that special tablet section in that issue. (I like how you did one
article on the color of tablets, it was the only color in the issue!)